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This review provides a summary of the global epidemiology of inflammatory bowel diseases IBD. It is now clear that IBD is increasing worldwide and has become a global emergence disease. Its incidence and prevalence in developing countries is steadily rising and has been attributed to the rapid modernization and Westernization of the population.

There is a need to reconcile the most appropriate treatment for these patient populations from the perspectives of both disease presentation and cost. In the West, biological agents are the fastest-growing segment of the prescription drug market. These agents cost thousands of dollars per patient per year. The healthcare systems, and certainly the patients, in developing countries will struggle to afford such expensive treatments.

The need for biological therapy will inevitably increase dramatically, and the pharmaceutical industry, healthcare providers, patient advocate groups, governments and non-governmental organizations should come to a consensus on how to handle this problem. The evidence that IBD is now affecting a much younger population presents an additional concern. Meta-analyses conducted in patients acquiring IBD at a young age also reveals a trend for their increased risk of developing colorectal cancer CRC , since the cumulative incidence rates of CRC in IBD-patients diagnosed in childhood are higher than those observed in adults.

IBD and its associated neoplastic transformation appear inevitable, which may significantly impact pediatric gastroenterology and adult CRC care. Due to an infrastructure gap in terms of access to care between developed vs.

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Former Disney executive resigns just months after appointment by Chinese video platform. Globalisation has, for many, undercut wages and jobs — and fuelled populism. Can three new books unpick an issue that so divides us? Efforts to challenge Elon Musk in US stepped up despite falling sales in pandemic. NBA postpones playoff games as anger grows over police shooting of black man in Kenosha.

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Prime minister confirms tax cuts while promising to eliminate debt burden within five years. Banks grappling with sub-zero rates are set for higher loan defaults, says board member Isabel Schnabel. Democracy is the norm across the continent, but soldiers are still seizing power.

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